I am the leader of the group "Bioavailability of fat-soluble vitamins ans micronutrients" (Human Micronutrition Team, "Nutrition, Obesity and Risk of Thrombosis" NORT laboratory).
I received an Engineer diploma in Nutrition and Food Sciences from Agrosup Dijon, France in 2002.
During my master degree and PhD thesis in the “Human Nutrition and Lipids” laboratory in Marseille, France, I studied carotenoid, vitamin A and E intestinal absorption. (We showed for the first time that lutein intestinal absorption was not a simple diffusion process but involved the membrane transporter SR-BI).
I then joined the working group of Dr. R.S. Molday in 2006 at the University of British Columbia in Vancouver, Canada to work on ATP transporter molecular functioning.
Back to Marseille, France since the end of 2008 in the “Nutrition, Obesity and Risk of Thrombosis” laboratory as a Researcher from the French National Institute of Agronomical Research, I currently focuses on fat-soluble vitamin and carotenoid absorption and membrane transport.
My research interests are: (i) the fate of fat-soluble vitamins and carotenoids in the human intestinal lumen; (ii) the effect of others (micro)nutrients on fat-soluble vitamins and carotenoids bioaccessibility (transfer to mixed micelles) and bioavailability (absorption by the intestine); (iii) the identification and the assessment of the respective contributions of membrane proteins in fat-soluble vitamin and carotenoid transport and (iv) the molecular functioning of the identified membrane transporters.
In vitro digestion, mixed micelle synthesis and characterisation, Caco-2 cell culture and cell transfection, biochemistry and molecular biology, gene expression, postprandial studies in rodents and humans
HPLC, granulometry, cell culture, animal and clinical study facilities
INRA (French National Institue of Agronomical Research)